Konsyl Pharmaceuticals, Inc., a leading producer of high quality, all natural fiber supplements for improving digestive health, offers Konsyl® Original as a powder-form, natural fiber supplement and bowel normalizer. Providing more fiber per dose than traditional bulk forming laxatives, Konsyl Original includes 6.0 grams of primarily soluble 100% psyllium fiber per dose. Additionally, Konsyl Original is sugar and sugar substitute-free, and contains no other additives or chemical stimulants.
Gentle and non-addictive, Konsyl Original effectively regulates the bowel without damaging the colon. Konsyl Original contains only 3 calories* per dose and requires fewer daily doses than other products. Safe for pregnant women and patients on gluten-free diets, Konsyl Original also benefits diabetes management, and contains the soluble fiber that has been proven to lower cholesterol levels.
Konsyl Original is available in fine pharmacies and chain stores throughout the United States. Konsyl products can also be purchased online at konsyl.
*Available calories
About Konsyl Pharmaceuticals, Inc.
Konsyl Pharmaceuticals, Inc. produces high quality, all natural fiber supplements for improved digestive health. Konsyl products treat a variety of digestive issues, such as constipation, hemorrhoids, diarrhea, IBS and diverticular disease. For over 45 years, doctors have recommended 100% natural Konsyl products as a soluble fiber supplement for patients of all ages. The high fiber content of Konsyl products helps consumers to achieve dependable digestive health. Konsyl products are available in fine pharmacies and chain stores throughout the United States.
For more information on Konsyl Pharmaceuticals, Inc. or its complete line of products, contact a company representative at 800-356-6795, or visit the company's website at konsyl.
суббота, 28 апреля 2012 г.
суббота, 21 апреля 2012 г.
If You Feel Unwell Stay At Home - Infection Control Advice From Addenbrooke's Hostpial, Cambridge, England
Norovirus, also known as winter vomiting, is a typical seasonal bug which appears when the colder weather sets in. Symptoms usually last 48 hours and include diarrhoea and vomiting. To protect vulnerable patients, the hospital is asking visitors feeling unwell to stay at home.
Cheryl Trundle, senior nurse for infection control, said: "Addenbrooke's, along with other hospitals in the region, is seeing an increase in patients presenting with suspected viral diarrhoea and vomiting. This is an acute illness which may come on suddenly but is usually over within 48 hours.
"We would advise that if you are affected you stay at home, drink plenty of fluids and follow good hygiene practices including hand washing. If you have been unwell or are feeling unwell you should not visit until you have been free from symptoms for at least 48 hours. This is to protect vulnerable patients in the hospital."
Source
David Williams
Press & Media Manager
addenbrookes.nhs
Cheryl Trundle, senior nurse for infection control, said: "Addenbrooke's, along with other hospitals in the region, is seeing an increase in patients presenting with suspected viral diarrhoea and vomiting. This is an acute illness which may come on suddenly but is usually over within 48 hours.
"We would advise that if you are affected you stay at home, drink plenty of fluids and follow good hygiene practices including hand washing. If you have been unwell or are feeling unwell you should not visit until you have been free from symptoms for at least 48 hours. This is to protect vulnerable patients in the hospital."
Source
David Williams
Press & Media Manager
addenbrookes.nhs
суббота, 14 апреля 2012 г.
Transarterial Embolization Is A Safe, Nonoperative Option For Acute Peptic Ulcer Bleeding
Researchers from China report that in patients with peptic ulcer bleeding in whom endoscopy failed to control the bleeding, transarterial embolization is a safe procedure which reduces the need for surgery without increasing overall mortality and is associated with few complications. The study appears in the May issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).
A peptic ulcer is an erosion in the lining of the stomach or the first part of the small intestine, called the duodenum. Normally, the lining of the stomach and small intestines are protected against the irritating acids produced in the stomach. If this protective lining stops working correctly, and the lining breaks down, it may result in inflammation (gastritis) or an ulcer. Small ulcers may not cause any symptoms. Some ulcers can cause serious bleeding.
Despite improvements in medical and endoscopic therapies for ulcers, bleeding may continue or recur in 13 percent of patients after endoscopic treatment for their bleeding peptic ulcers. Continued bleeding after initial treatment often leads to a need for surgery, but the surgery is associated with a high morbidity rate (55 percent) and a high mortality rate (30 percent). Transarterial embolization (TAE) has been proposed as an alternative to this type of surgery. Angiography with TAE provides a nonoperative option for patients whose acute peptic ulcer bleeding has not been controlled by endoscopy. Embolization is a treatment that clogs small blood vessels and blocks the flow of blood, and agents used for this purpose include Gelfoam, polyvinyl alcohol, cyanoacrylic glues, and coils. Primary technical success rates range between 52 percent and 98 percent, with recurrent bleeding requiring repeated embolization procedures in approximately 10 percent to 20 percent of patients.
"In our study, we set out to compare the outcomes of transarterial embolization and salvage surgery for patients with peptic ulcers in whom endoscopic hemostasis failed," said study lead author Tiffany Cho-Lam Wong, The Institute of Digestive Disease, The Chinese University Hong Kong. "We found TAE is a safe procedure with a high technical success rate. In those with gastroduodenal ulcer bleeding in whom endoscopic hemostasis failed, TAE reduces the need for surgery and the overall complications, and accomplishes this without increasing the overall mortality."
Methods
This was a retrospective study of patients admitted to the Prince of Wales Hospital at the Chinese University of Hong Kong. Data were retrieved from a prospectively-collected GI bleeding registry. Consecutive patients admitted with overt signs of upper GI bleeding received endoscopy within 24 hours after admission. Patients were under the joint care of surgeons and gastroenterologists. "Salvage" intervention (either surgery or TAE) was deemed to be warranted if active bleeding could not be controlled by endoscopic means or if a patient had a second rebleeding episode. The main outcomes measurements were all-cause mortality, rebleeding, reintervention, and complication rate.
Results
Thirty-two patients underwent TAE and 56 underwent surgery. In those who underwent TAE, the bleeding vessels were the gastroduodenal artery (25 patients), left gastric artery (4 patients), right gastric artery (2 patients), and splenic artery (1 patient). Active extravasation (blood flowing from a vessel into surrounding tissue) was seen in 15 patients (46.9 percent). Embolization was attempted in 26 patients, and angiographic coiling was successful in 23 patients (88.5 percent). Bleeding recurred in 11 patients (34.4 percent) in the TAE group and in 7 patients (12.5 percent) in the surgery group. More complications were observed in patients who underwent surgery (40.6 percent vs. 67.9 percent). There was no difference in 30-day mortality (25 percent vs. 30.4 percent), mean length of hospital stay (17.3 vs. 21.6 days), and need for transfusion (15.6 vs. 14.2 units) between the TAE and surgery groups.
The researchers noted that their cohort of patients represented the highest risk group. The mean age of patients was 73.1 years and 71.1 years in TAE and surgery groups, respectively, and 87.5 percent of the patients had more than one comorbidity.
In conclusion, the researchers stated that their study findings led them to reassess the role of surgery and current management algorithms for peptic ulcer bleeding. TAE should be considered, if not before, then at least as an alternative to surgery in patients with peptic ulcer bleeding in whom primary endoscopic hemostasis fails or in those who developed a second rebleeding episode.
"Despite the retrospective, observational design of this study, Wong et al provide important, clinically relevant data that advance our knowledge of how we should be caring for patients with peptic ulcer bleeding," said Ian M. Gralnek, MD, MSHS, FASGE, Rappaport Family Faculty of Medicine, Technion-Israel Institute of Technology, Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel, in an accompanying editorial.
Source:
Anne Brownsey
American Society for Gastrointestinal Endoscopy
A peptic ulcer is an erosion in the lining of the stomach or the first part of the small intestine, called the duodenum. Normally, the lining of the stomach and small intestines are protected against the irritating acids produced in the stomach. If this protective lining stops working correctly, and the lining breaks down, it may result in inflammation (gastritis) or an ulcer. Small ulcers may not cause any symptoms. Some ulcers can cause serious bleeding.
Despite improvements in medical and endoscopic therapies for ulcers, bleeding may continue or recur in 13 percent of patients after endoscopic treatment for their bleeding peptic ulcers. Continued bleeding after initial treatment often leads to a need for surgery, but the surgery is associated with a high morbidity rate (55 percent) and a high mortality rate (30 percent). Transarterial embolization (TAE) has been proposed as an alternative to this type of surgery. Angiography with TAE provides a nonoperative option for patients whose acute peptic ulcer bleeding has not been controlled by endoscopy. Embolization is a treatment that clogs small blood vessels and blocks the flow of blood, and agents used for this purpose include Gelfoam, polyvinyl alcohol, cyanoacrylic glues, and coils. Primary technical success rates range between 52 percent and 98 percent, with recurrent bleeding requiring repeated embolization procedures in approximately 10 percent to 20 percent of patients.
"In our study, we set out to compare the outcomes of transarterial embolization and salvage surgery for patients with peptic ulcers in whom endoscopic hemostasis failed," said study lead author Tiffany Cho-Lam Wong, The Institute of Digestive Disease, The Chinese University Hong Kong. "We found TAE is a safe procedure with a high technical success rate. In those with gastroduodenal ulcer bleeding in whom endoscopic hemostasis failed, TAE reduces the need for surgery and the overall complications, and accomplishes this without increasing the overall mortality."
Methods
This was a retrospective study of patients admitted to the Prince of Wales Hospital at the Chinese University of Hong Kong. Data were retrieved from a prospectively-collected GI bleeding registry. Consecutive patients admitted with overt signs of upper GI bleeding received endoscopy within 24 hours after admission. Patients were under the joint care of surgeons and gastroenterologists. "Salvage" intervention (either surgery or TAE) was deemed to be warranted if active bleeding could not be controlled by endoscopic means or if a patient had a second rebleeding episode. The main outcomes measurements were all-cause mortality, rebleeding, reintervention, and complication rate.
Results
Thirty-two patients underwent TAE and 56 underwent surgery. In those who underwent TAE, the bleeding vessels were the gastroduodenal artery (25 patients), left gastric artery (4 patients), right gastric artery (2 patients), and splenic artery (1 patient). Active extravasation (blood flowing from a vessel into surrounding tissue) was seen in 15 patients (46.9 percent). Embolization was attempted in 26 patients, and angiographic coiling was successful in 23 patients (88.5 percent). Bleeding recurred in 11 patients (34.4 percent) in the TAE group and in 7 patients (12.5 percent) in the surgery group. More complications were observed in patients who underwent surgery (40.6 percent vs. 67.9 percent). There was no difference in 30-day mortality (25 percent vs. 30.4 percent), mean length of hospital stay (17.3 vs. 21.6 days), and need for transfusion (15.6 vs. 14.2 units) between the TAE and surgery groups.
The researchers noted that their cohort of patients represented the highest risk group. The mean age of patients was 73.1 years and 71.1 years in TAE and surgery groups, respectively, and 87.5 percent of the patients had more than one comorbidity.
In conclusion, the researchers stated that their study findings led them to reassess the role of surgery and current management algorithms for peptic ulcer bleeding. TAE should be considered, if not before, then at least as an alternative to surgery in patients with peptic ulcer bleeding in whom primary endoscopic hemostasis fails or in those who developed a second rebleeding episode.
"Despite the retrospective, observational design of this study, Wong et al provide important, clinically relevant data that advance our knowledge of how we should be caring for patients with peptic ulcer bleeding," said Ian M. Gralnek, MD, MSHS, FASGE, Rappaport Family Faculty of Medicine, Technion-Israel Institute of Technology, Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel, in an accompanying editorial.
Source:
Anne Brownsey
American Society for Gastrointestinal Endoscopy
суббота, 7 апреля 2012 г.
Ulcer Rebleeding Best Prevented By Empirical H. Pylori Treatment
H. pylori eradication was superior to any other strategy for preventing recurrence after an episode of ulcer bleeding. In addition, immediate empirical antibiotic treatment was more effective and cheaper than performing H. pylori tests and treating only patients with a positive result.
A recent cost-effectiveness analysis performed by Dr Emili Gen?© and co-workers, researchers of the CIBERehd at the Hospital de Sabadell, was aimed to determine the most efficacious strategy for preventing recurrence of peptic ulcer bleeding.
The two H. pylori treatment strategies evaluated in the study were superior to non-treatment approaches for preventing rebleeding. When both of them were compared, empirical antibiotics were clearly better than test-guided treatment to prevent bleeding recurrence being both cheaper and more effective.
Haemorrhage is the most frequent complication of peptic ulcer disease and is associated with substantial morbidity, mortality and costs. Improvements on its management and prevention are, therefore, of paramount importance.
"H pylori infection is still the most important cause of ulcer bleeding. Starting empirical antibiotic during admission for bleeding would increase adherence to treatment. In addition, it avoids undertreatment because of the false negative H pylori tests that are very frequent in this setting" said Dr. Xavier Calvet, co-author of the study, which will appear in a future issue of Value in Health, the official journal of the International Society of Pharmacoeconomics and Outcomes Research (ISPOR).
Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research and help health care leaders to make decisions that are solidly evidence-based. The journal is published bi-monthly and has a regular readership of over 4,000 clinicians, decision-makers, and researchers worldwide.
ISPOR is a nonprofit, international organization that strives to translate pharmacoeconomics and outcomes research into practice to ensure that society allocates scarce health care resources wisely, fairly, and efficiently.
Source
ISPOR
A recent cost-effectiveness analysis performed by Dr Emili Gen?© and co-workers, researchers of the CIBERehd at the Hospital de Sabadell, was aimed to determine the most efficacious strategy for preventing recurrence of peptic ulcer bleeding.
The two H. pylori treatment strategies evaluated in the study were superior to non-treatment approaches for preventing rebleeding. When both of them were compared, empirical antibiotics were clearly better than test-guided treatment to prevent bleeding recurrence being both cheaper and more effective.
Haemorrhage is the most frequent complication of peptic ulcer disease and is associated with substantial morbidity, mortality and costs. Improvements on its management and prevention are, therefore, of paramount importance.
"H pylori infection is still the most important cause of ulcer bleeding. Starting empirical antibiotic during admission for bleeding would increase adherence to treatment. In addition, it avoids undertreatment because of the false negative H pylori tests that are very frequent in this setting" said Dr. Xavier Calvet, co-author of the study, which will appear in a future issue of Value in Health, the official journal of the International Society of Pharmacoeconomics and Outcomes Research (ISPOR).
Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research and help health care leaders to make decisions that are solidly evidence-based. The journal is published bi-monthly and has a regular readership of over 4,000 clinicians, decision-makers, and researchers worldwide.
ISPOR is a nonprofit, international organization that strives to translate pharmacoeconomics and outcomes research into practice to ensure that society allocates scarce health care resources wisely, fairly, and efficiently.
Source
ISPOR
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